Cabozanib 20mg (Cabozantinib)

What is Cabozanib 20mg?

Cabozanib 20 mg contains its active ingredient Cabozantinib, which is a targeted therapy for cancer, used mostly for the treatment of various advanced cancers that include renal cell cancer (RCC), Hepatocellular Cancer (HCC), and medullary thyroid cancer (MTC).

Cabozantinib is a tyrosine-kinase inhibitor (TKI), blocking cancer-causing enzymes and blood vessel development (angiogenesis) and cancer cell survival. It helps to stop the progression of cancer.

How Does Cabozanib 20mg Work?

Cabozantinib blocks multiple tyrosine kinases, including VEGFR, MET, and AXL. These proteins are crucial in the signalling pathway that encourages the growth of tumors and blood vessel development (angiogenesis). Through blocking these pathways, caboozanib deprives cancer of oxygen and nutrients and reduces its capacity to expand and grow.

Why Choose Cabozanib 20mg?

• Targeted therapy: Specifically designed to block signals from cancer cells.
• Multiple cancer types: Appropriate for liver, kidney, and thyroid cancers.
• Oral administration: The capsule is convenient and allows patients to receive treatment outside of the hospital.
• Improved outcomes: Clinical trials have shown an increase in the rate of progression-free survival, as well as survival overall, among patients being treated.

Uses and Benefits of Cabozanib 20mg

Renal Cell Carcinoma (RCC)

In patients suffering from metastatic or advanced RCC, especially after previous treatment.

Hepatocellular Carcinoma (HCC)

Accepted by patients suffering from advanced liver cancer. Usually, this follows other treatment.

Medullary Thyroid Cancer (MTC)

The treatment option available to treat metastatic MTC.

Dosage and How to Take Cabozanib 20mg

• A typical dose for starting is 60mg daily; however, the dosage can be adjusted by your physician according to your response and tolerance. The strength of the capsule is 20 mg, which allows for an adjustable dose.
• Use Cabozanib in a liquid form, whether or not food is included.
• Take capsules in whole form. Do not crush them or chew.
• Beware of grapefruit and grapefruit juice because they may affect the metabolism of certain drugs.

Side Effects of Cabozanib 20mg

Common Side Effects

• Diarrhoea
• Fatigue
• Decreased appetite
• Hand-foot syndrome (redness, pain on palms/soles)
• High blood pressure

Serious Side Effects (Seek medical advice immediately)

• Severe bleeding
• Gastrointestinal perforation
• Blood clots
• Liver toxicity

Precautions and Contraindications

• It is not recommended for those with chronic hypertension that is not controlled or who have had recent bleeding incidents.
• A regular blood pressure check and monitoring of liver function are required.
• Be sure to inform your doctor about any medicines you take to prevent interactions.

Cabozanib 20mg Compared to Other Tyrosine Kinase Inhibitors (TKIs)

Storage Instructions

• Place the items in a cool and dry area in a dark, dry place away from direct sunlight.
• Be sure to keep away from young children.
• Use only up to the expiration date.

Frequently Asked Questions (FAQs)

1. What is Cabozanib 20mg used for?

It’s utilized to treat advanced liver, kidney, and thyroid cancers by inhibiting the growth pathways of tumours.

2. How does Cabozanib work?

Inhibiting enzymes that stimulate the growth of cancer cells and blood vessel development.

3. What should I do if I miss a dose?

Get it in as fast as you are able, even if it’s not too far away from the time you’ll need to take your next dose. Do not take more than one dose.

4. Can Cabozanib be taken with food?

Yes, Absolutely, and with or without food.

5. What are the common side effects?

Fatigue, diarrhoea, and a reduced appetite, along with hand-foot symptoms.

6. Are there serious risks?

Yes, absolutely, this includes the liver, bleeding, and blood clots. Seek urgent medical attention in the event of these.

7. Can I drink alcohol while taking Cabozanib?

Drinking alcohol may cause more adverse effects. Talk to your physician.

8. How often will I need monitoring?

The regular blood pressure test, the liver function, and the results of blood tests are monitored when treating.

9. Is Cabozanib safe during pregnancy?

No, the risk is that it can affect the foetus. Use effective contraception.

10. Can Cabozanib be used with other cancer drugs?

At times, however, only when under the direction of a specialist.