Susten 100mg Injection (Progesterone)

Overview

Susten 100mg Injection is a progesterone-based medicine used for support during pregnancy, especially for women who undergo assisted reproductive technology (ART), including IVF (IVF). Progesterone is an organic hormone that plays an important role in the regulation of the menstrual cycle as well as maintaining pregnancy. It is responsible for preparing the endometrium (lining of the uterus) to facilitate the birth of fertilized eggs and aids in the initial phases of pregnancy by stopping the uterus from contracting too early.

• Active Ingredient: Progesterone 100mg per injection.

Drug Class:

• Hormone Therapy (Progestin)

Indications:

Susten 100mg Injection is recommended to treat the following ailments:

1. Progesterone Supplementation:
   • It is used to boost progesterone levels in early gestation, especially for women who are suffering from inadequate progesterone levels or who are going through fertility treatment (like IVF).
2. Hormonal Support in Assisted Reproductive Technologies:
   • Injections are given to women who undergo in vitro fertilization (IVF) as well as other assisted reproduction techniques (ART) to aid the luteal stage of the menstrual cycle following the ovulation period, and also during pregnancy.
3. Menstrual Disorders:
   • Occasionally used to treat abnormal bleeding from the uterus caused by hormone imbalances.
4. Prevention of Miscarriage:
   • In some instances, it is used in certain cases to stop the possibility of miscarriage for women who have a history of repeated pregnancies due to progesterone deficiency.
5. Hormonal Therapy for Menopause:
   • Sometimes, it is used as a hormonal replacement therapy (HRT) for women who are menopausal to reduce the risk of the development of endometrial hyperplasia (thickening of the inner lining of the uterus).

Mechanism of Action:

• Progesterone is a natural hormone, a steroid that plays an important role in the menstrual cycle as well as pregnancy. If administered in the form of an injection, progesterone:
  • Prepares the Uterus: The endometrium gets thicker (the lining that surrounds the uterus) and allows the fertilized egg to grow and flourish.
  • Maintains Pregnancy: Reduces the risk of uterine contractions and thus helps the baby throughout its early stages.
  • Regulates Menstrual Cycle: Progesterone helps to counteract the effect of estrogens on the lining of the uterus and regulates the menstrual cycle.

In addition to boosting progesterone levels for women who have hormonal imbalances, as well as during ART procedures, Susten 100mg injection provides an ideal environment for early conception and pregnancy.

Dosage and Administration:

• Route of Administration: Intramuscular (IM) injection.
• Recommended Dosage:
  • For Fertility Treatments (IVF or ART): A typical dose ranges from 100 mg to 200 mg administered intramuscularly every day, usually beginning with the day of ovulation or embryo transfer through the 10th week of gestation.
  • For Pregnancy Support: The amount and duration of the dosage can vary according to the person’s medical condition. It can be maintained for a period of time to maintain adequate levels of progesterone in pregnancies.
  • For Menstrual Disorders or Endometrial Support: 50mg-100mg can be given during specific days during the menstrual period when directed by a healthcare provider.
• Administration Instructions:
  • The injection must be administered to the muscles deep (usually the gluteal muscles).
  • If you’re administering the injection on your own or having someone else does it for you, make sure you follow the correct procedure in order to avoid injury or irritation.
  • Make sure to rotate injection sites in order to prevent discomfort to the tissues and also ensure a uniform absorption.
• Missed Dose:
  • If the dose was missed, it should be administered in the shortest time possible. If the time is near to take the next dose, do not take the missed dose. Don’t administer two doses in one go.

Side Effects:

Common side effects include:

• Pain at Injection Site: The injection may result in irritation, redness, or swelling around the site of injection.
• Fatigue: A few women complain of tiredness or fatigue after an injection.
• Headache: Progesterone may cause migraines and headaches.
• Breast Tenderness: A greater sensitivity or discomfort is felt within the breasts.
• Mood Changes: Hormonal changes can cause anxiety, mood swings, or or irritability.
• Dizziness or Drowsiness: Progesterone could cause dizziness or the feeling of sedation for some people.
• Nausea: A few people might experience stomach discomfort, nausea, or vomiting.

Less common but serious side effects:

• Severe Allergic Reaction: Rash, itching, swelling, and difficulty breathing.
• Blood Clots: The symptoms include swelling, pain, swelling in the legs, and sudden chest pains, or breathlessness, which could mean the presence of a blood clot.
• Heavy Bleeding: Spotting or bleeding that is unusual may be a sign of problems within the uterine lining or an underlying problem.
• Liver Dysfunction: The signs include jaundice (yellowing of the skin or eyes), abdominal pain, or bloody urine.

Contraindications:

Susten 100mg Injection shouldn’t be avoided to be utilized in the following scenarios:

• Allergic Reactions: Patients who are allergic to progesterone or another substance in the medicine.
• Unexplained Vaginal Bleeding: In women who experience irregular vaginal bleeding, the causes are not clear.
• Severe Liver Disease: Patients with liver diseases that are active or conditions that severely interfere with liver function.
• Thromboembolic Disorders: The history of blood clotting disorders, or thrombophlebitis.
• Hormone-Sensitive Cancers: Breast cancer patients and endometrial cancer or any other hormonally-related tumors must avoid taking progesterone supplements unless specifically ordered by a physician.

Drug Interactions:

Progesterone (Susten) could interfere with various types of drugs, such as:

• Anticoagulants: Progesterone could enhance the results of blood thinners, thereby increasing the chance of bleeding.
• Corticosteroids: The combination of corticosteroids with progesterone may raise the chance of adverse effects. These include swelling of the blood pressure.
• Anticonvulsants: Certain anticonvulsants can affect the efficiency of progesterone because they increase the metabolism of the liver.
• Other Hormonal Medications: The combination of other hormone therapies could result in a hormonal imbalance or an increase in negative side effects.

It is important to notify your doctor of all medications you’re taking, such as over-the-counter medications as well as supplements.

Storage:

• Temperature: Store at room temperature (15°C to 30°C / 59°F to 86°F).
• Avoid Freezing: Don’t freeze the injection.
• Keep Out of Reach of Children: Keep the items out of the kids’ reach to avoid accidental consumption.

FAQs:

What is Susten 100mg used for?

Susten 100mg Injection is utilized to boost progesterone levels during fertility treatments for supporting pregnancy, as well as dealing with irregular menstrual cycles. Susten is also utilized to stop miscarriage among women who have low levels of progesterone.

How is Susten 100mg injected?

Susten 100mg dose is given via intramuscular injection (into the muscles) generally within the gluteal region (buttocks). A trained healthcare professional or person can administer this injection.

What should I do if I miss a dose of Susten?

If you are unable to take a dose, get it back immediately if you can, until it’s time to take the next dose. Avoid taking two injections simultaneously.

Can I self-administer Susten 100mg?

Yes, if you have been properly trained by your doctor, you can administer the injection. Make sure you adhere to the procedure and turn the injection site so that you don’t experience any discomfort.

What are the common side effects of Susten 100mg?

The most common side effects are injection discomfort and fatigue. Other common side effects include headaches, fatigue, and feelings of tenderness in the breast, mood fluctuations, dizziness, and nausea.

Can I use Susten 100mg during early pregnancy?

Yes, Susten 100mg can indeed be widely used to aid pregnant women who have progesterone deficiencies. Your physician will instruct you in the dose and the duration.

Is there any risk of blood clots with Susten 100mg?

Yes, there is the possibility of blood clots arising from the use of progesterone, especially in women who have a history of blood clots.

Can I use Susten 100mg if I am breastfeeding?

Progesterone is usually considered to be safe for the breastfeeding period. But it is important to talk to your doctor before taking any medications while you are breastfeeding.

Summary:

Susten 100mg Injection is a therapy based on progesterone that is used to treat fertility issues, early pregnancy assistance, and menstrual issues. It can help women with the deficiency of progesterone deficiency maintain a good pregnancy or control their menstrual cycles. When administered intramuscularly, it’s beneficial in stopping miscarriage as well as supporting in vitro fertilization (IVF), and managing problems with the endometrium. Though generally safe, the potential adverse effects could be pain at the injection site as well as dizziness and fatigue. It is important to adhere to the medical advice and notify your doctor about any other medication you’re taking.